Daytrana Delivers Benefits Parents Can See
Based on parent ratings, Daytrana® significantly reduced ADHD symptoms.
Parents reported significant improvement in symptoms with Daytrana at 4 hours and 8 hours after application as compared with placebo patch.
- 51% reduction in ADHD symptoms with Daytrana
Mean Conners Parent Rating Scale-R Scores by Time Point
Study 302: A 7-week randomized, double-blind placebo-controlled, parallel-group study of methylphenidate transdermal system in pediatric patients with ADHD Patch applied at 7 AM. Measurements at 11 AM and 3 PM. Least squares mean change from baseline to end point in Conners' Parent Rating Scale total score.
- Daytrana was statistically significant as compared with placebo patch
- The most common adverse events associated with the Daytrana patch in this study were decreased appetite, insomnia, nausea, vomiting, and weight loss. Mild erythema at the patch site was common and almost all patients reported no evidence or minimal evidence of irritation. Two patients treated with Daytrana discontinued due to application site reactions
*P=.0001 for Daytrana vs placebo.
Adapted from Findling RL, Bukstein OG, Melmed RD, Lopez FA, et al. J Clin Psychiatry. 2008; 69:149-159.
Video: Applying and Removing the Patch